Dr. Ng Shyh-Chang is the PI of the Stem Cell and Regenerative Metabolism Lab at the Institute of Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, and Professor at the University of Chinese Academy of Sciences.

He graduated with an A.B. (highest honors) from Princeton University, and a Ph.D. from Harvard Medical School, before becoming a PI at the Genome Institute of Singapore. He was one of the early pioneers in the field of stem cell metabolism, with a focus on the metabolic changes required for stem cell differentiation and tissue regeneration. In his earlier work, he found that adult mammals, including humans, possess a dormant gene that promotes the juvenile state, Lin28. This stem cell factor can regulate mitochondrial metabolism in a unique fashion to promote regeneration in a variety of damaged tissues. Dr. Ng's team also achieved another breakthrough in the study of muscle stem cell metabolism and exploited its therapeutic windows in metabolism to treat muscle wasting disorders. His findings have been published in Science, Nature, Nature Medicine, Cell, Cell Stem Cell, Cell Metabolism, Cell Proliferation, Cell Reports, Genes Dev, Development and other journals. He has won numerous accolades, including the VcanBio Prize for Biomedical Breakthroughs, CAS Person of the Year, and the Howard Hughes Medical Institute (HHMI)-Gates Foundation International Scholar.